Mathematical bio-medicine and survival analysis.
Statistical mechanics of disordered many-particle systems.
Processes on complex networks and random graphs. |
Topics and projects
I am involved in
the creation of a multidisciplinary research and teaching
infrastructure at King's College London, to combine and exploit expertise at the
interfaces between biology, medicine, physics, computer science and
mathematics. See the websites of the
Institute for Mathematical and Molecular Biomedicine and the
Systems Biomedicine Graduate Programme. A brief nontechnical introduction to the role of mathematics
in cancer research can be found
Medical statistics: Bayesian
analysis of survival data in presence of cohort heterogeneity
and competing risks
- Mathematical immunology:
dynamics and statics of large
immune system networks in the finite connectivity regime
Theory of cellular
signaling processes in e.g. proteomic, gene regulatory, and metabolic networks
Analysis of sparse random graph ensembles
Equilibrium and non-equilibrium
theory of processes on complex finitely connected graphs
primary/secondary/tertiary structure generation in hetero-polymers
Calculation of the stationary
state probability distribution for non-detailed balance spin
Dynamics of econophysical models
such as minority games, describing cooperative phenomena in
Research and review papers
There is a full list of my
publications, and you can find PDFs of
recently published papers (from 2000 onwards),
either organized by year or
In addition the following recent preprint(s) can be downloaded:
- E Agliari, A Annibale, A Barra, ACC Coolen and D Tantari
Immune networks: multi-tasking capabilities at near saturation
(accepted for publication in J Phys A, PDF)
- J Barrett and ACC Coolen
Dimensionality detection and integration of multiple data
sources via the GP-LVM
(submitted to Journal of Machine Learning Research, PDF)
- J van Baardewijk, H Garmo, M van Hemelrijck, L Holmberg and ACC Coolen
Generic solution of the heterogeneity-induced
competing risk problem in survival analysis
(submitted to Journal of the Royal Statistical Society B, PDF)
Mathematical theory of minority games - statistical mechanics of
(Oxford University Press, January 2005)
(click here for preface and
detailed list of contents)
ACC Coolen, R Kuehn and P Sollich
of neural information processing systems
(Oxford University Press, July 2005)
for preface and detailed list of contents)
ACC Coolen and L Holmberg
Principles of survival analysis
(Oxford University Press, 2013/14)
ACC Coolen, A Annibale and K Roberts
Generating random networks and graphs
(Oxford University Press, 2013/14)
Recent research talks and seminars
22 December 2003
"The trick which became a theory: a
brief history of the replica method"
21 January, and Tokyo, 3 February 2004
(soft) spin systems on random graphs with finite connectivity"
1 April 2004
"Simple solvable models of primary and
secondary structure formation in hetero-polymers"
27 September 2004, and Amsterdam, 12 November 2004
functional analysis of minority games with real market histories"
26 May 2005
"Theory of coupled oscillators on finitely
connected random networks"
3 June 2005
"Statistical mechanics of signalling
processes on complex biological networks"
10 June 2005
"Generating functional analysis of
minority games with inner product strategy definitions"
8 August 2005
"Finitely connected vector spin systems
with random matrix interactions"
10 Jan 2006
"Dynamics on finitely connected random
27 Sept 2006
"Generating functional analysis of inner
product minority games"
8 Nov 2007
"Applications of generating functional
analysis to minority game models"
16 Jan 2008
"Spin models on random graphs with
controlled topologies beyond degree constraints"
13 Feb 2008
"A solvable model of the genesis of
amino-acid sequences via coupled dynamics of folding and slow
16 Sep 2009
"Generating functional analysis of complex
formation and dissociation in large protein interaction networks"
- London, 21 Oct 2009
"Protein interaction networks viewed through
statistical mechanical glasses"
- Stockholm (NORDITA), 22 June 2010, and Rome (La Sapienza), 1 July 2010
"Tailoring, counting, and generating sructured random graphs"
- Dublin, 22 June 2011
"Analysis of signalling in large protein interaction networks"
- Evora (Portugal), 16 Sept 2011
"Controlled Markovian dynamics of graphs"
- London, 21 Feb 2012, 26 March 2012
"What you see is not what you get: how sampling affects macroscopic features of
- Stockholm, 12 June 2013
"Generic solution of the competing risk problem in survival analysis"